Women and communities of color have been disproportionately harmed by COVID-19. Women are overrepresented in the front-line workforce, making up the majority of workers risking their lives to provide health care, child care, and other essential services—yet women are also more likely than men to be losing their jobs. Black, Latinx, and Native American people are also disproportionately facing unemployment, and are contracting and dying from COVID-19 at higher rates than white people due to structural inequities in access to health care and economic security. Asian communities are facing a new wave of discrimination, and in some places are experiencing disproportionately high rates of infection as well. And for Black women, Latinas, Native American women, Asian American/Pacific Islander women, and other women of color, intersecting marginalized identities heighten their risk of facing economic distress, unemployment, and poor health outcomes. While the virus doesn’t discriminate, its impacts reflect and amplify centuries of discrimination.